Nerve Growth Factor Gene Therapy
نویسندگان
چکیده
منابع مشابه
Nerve growth factor in human semen: Effect of nerve growth factor on the normozoospermic men during cryopreservation process
Objective(s):Althoughroutinely applied in assisted reproductive technology, human sperm cryopreservation is not a completely successful procedure. Adverse effects of cryopreservation on the fertilization capacity, motility, morphology, and viability of spermatozoa have been proven; cryopreservation has also shown a role in sperm DNA fragmentation and infertility. The post-thaw survival of sperm...
متن کاملNerve Growth Factor Gene Therapy: Activation of Neuronal Responses in Alzheimer Disease.
IMPORTANCE Alzheimer disease (AD) is the most common neurodegenerative disorder and lacks effective disease-modifying therapies. In 2001, we initiated a clinical trial of nerve growth factor (NGF) gene therapy in AD, the first effort at gene delivery in an adult neurodegenerative disorder. This program aimed to determine whether a nervous system growth factor prevents or reduces cholinergic neu...
متن کاملNerve Growth Factor: A Focus on Neuroscience and Therapy.
Nerve growth factor (NGF) is the firstly discovered and best characterized neurotrophic factor, known to play a critical protective role in the development and survival of sympathetic, sensory and forebrain cholinergic neurons. NGF promotes neuritis outgrowth both in vivo and in vitro and nerve cell recovery after ischemic, surgical or chemical injuries. Recently, the therapeutic property of NG...
متن کاملNerve Growth Factor
Nerve growth factor (NGF) is a signaling protein [4] and growth factor implicated in a wide range of development and maintenance functions. NGF was discovered through a series of experiments in the 1950s on the development of the chick [5] nervous system. Since its discovery, NGF has been found to act in a variety of tissues throughout development and adulthood. It has been implicated in immune...
متن کاملNerve Growth Factor
Nerve growth factor (NGF) is a signaling protein [4] and growth factor implicated in a wide range of development and maintenance functions. NGF was discovered through a series of experiments in the 1950s on the development of the chick [5] nervous system. Since its discovery, NGF has been found to act in a variety of tissues throughout development and adulthood. It has been implicated in immune...
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ژورنال
عنوان ژورنال: JAMA Neurology
سال: 2015
ISSN: 2168-6149
DOI: 10.1001/jamaneurol.2015.1807